It's been a long, long time since everything was animated by hand. It's even been quite some time since ANYTHING was actually animated by hand, probably late 90s, very early 00s at the latest. Nowadays, for a series like this, it's mostly just for storyboarding, static backgrounds and character key frames, and even for those last two, they make heavy use of digital art programs to simplify the process.
Money makes a world of difference. Because more money lets you hire more, better and more experienced artists, lets you outsource the tweening to the best dedicated studios (or, God, forbid, even hire or assemble one in Japan), lets you pay your staff properly so they can focus on their work without having to worry about paying rent, lets you flood your studio with PAs to take care of all the little things, lets you work with the latest equipment without having people need to take shifts on it, lets you buy time on the fastest rendering farms so you don't have to wait ages for everything to see the results, etc, etc.
Anime production has long been chronically underfunded and overworked, even for the really big productions, one of the reasons it has become hard to find and keep good staff. No matter how much money a series makes, the studios that actually create it are effectively treated as a contractor, and generally get a set amount of money regardless (perhaps with a little bonus, if they are lucky). All the actual money goes to the production committee, which is generally composed of the company holding the rights to the original source material and various investment groups.
It's a vicious cycle: they get hired by a production committee on a contract basis, which they need to take to keep the lights on, but then they get paid so little that they don't have the cash to fund the development of their own independent series, so they once again have to hope to get another offer from a production committee on a contract basis.
Even in the occasional case where they do manage to self-fund the production of an anime based on a new IP that they will hold the rights to, it's usually a huge gamble, because if it isn't sufficiently successfully, it could mean the end for them. A contract job at least ensures they will get paid as long as they deliver, but an underperforming independent production will generally mean bankruptcy, as they don't have any financial safety net to fall back on.
So yeah, money, or, more specifically, the absence of money, is one of the major issues faced by the anime production industry right now. They can't afford enough staff, or to pay the staff they do have a proper living wage. They can't afford not to put the staff they do have through hellish hours that make the crunch controversy in Western gene development seem like a joke in comparison. They can't afford the technology that could make production easier. They can't afford to hire local tweeners, forcing them to outsource to foreign studios, resulting in frequent miscommunication due to language issues. Even if they could afford more staff, they usually wouldn't be able to afford the extra office space or equipment needed. Etc, etc.
Money is definitely the biggest issue right now, and is the direct cause of most of the next-biggest issues. The industry is cannibalizing itself, crushing the actual people making anime underfoot to provide profits to the investors in the production committees, resulting in fewer and fewer people entering, and staying with, the industry. It's not a sustainable system, and something needs to change, ideally yesterday.